In the years and years Mythbusters has been on, Adam and Jamie have moved from actual myths (Pop Rocks and Coke) to vague sciencey-wonderings (what if we replicated a second-season episode...slightly differently!) but have stayed away from video game myths. I'm guessing that's because video games all take place in artificial worlds with the physics coded in, so investigating if a car can handle the way in does in a Gran Turismo game is a bit like "investigating" if a painting of Mick Jagger actually looks like Mick Jagger. It probably does, and where it doesn't is due to artistic style/limitations, not anything inherently weird in Mick Jagger.
But there remains a wealth of gaming oddness that one could successfully explore in televised form, and Proving Ground (on the G4 Channel, which I've heard rumors that some people actually get) is where that will happen. Its first episode, in fact, checks out Super Mario Kart, the competitor for Gran Turismo for down-to-the-pixel faithful reconstructions of precision automotive equipment. And bananas.
According to the USA Today preview, the Mario Kart demonstration works for the Proving Ground crew -- which I'm guessing means that throwing crap from a go-kart at someone else will actually hit them. Star Wars, it turns out, doesn't: pleasepleaseplease cut to them testing the Force a la Silent Bob in Mallrats.